Τίτλος:
THE IMPACT OF SCATTERING AND PEAK SPECTRUM OF I-123 IN SCINTIGRAPHY BY
I-123 MIBG
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Metaiodobenzylguanidine (MIBG) scintigraphy is used to image tumors of
neuroendocrine origin and study disorders of sympathetic innervation of
the myocardium. Scintigraphic imaging methods offer the possibility of
qualitative and quantitative assessment of tracer concentration.
Accurate correction for the physical degrading factors (attenuation,
scatter, partial volume effects) is demanded. An analytical study of the
I-123 energy spectrum, scattering and attenuation contribution to the
resulting image of an I-123 MIBG scintigraphy, has been undergone, so as
to improve the data that could be collected by I-123-MIBG use. In this
work, quantitative data were gathered at various source depths, volumes
and crystal to phantom distances to determine the effect of these
variables on source activity data. The final image is being extracted
from the combination of three different images, each and every one being
acquired by a different energy window. The middle one has been obtained
from the main I-123 photopeak and the others, from the left and right
peaks respectively. The problem of Compton scattering as the dominant
photon interaction phenomenon and its impact on both the quality of
clinical images and the accuracy of quantitative analysis is taken into
consideration for a scatter modeling in non-uniform media.
Συγγραφείς:
Lyra, M. E.
Lagopati, N.
Sotiropoulos, M.
Chatzigiannis, Ch.
and Gavrilelli, M.
Εκδότης:
WORLD SCIENTIFIC PUBL CO PTE LTD
Τίτλος συνεδρίου:
ADVANCED TOPICS IN SCATTERING THEORY AND BIOMEDICAL ENGINEERING
DOI:
10.1142/9789814322034_0008
