Τίτλος:
Comparison of Muscle Functional Electrical Stimulation to Conventional
Bicycle Exercise on Endothelium and Functional Status Indices in
Patients With Heart Failure
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The aim of this prospective, open-label, cohort study was to compare the
effect of muscle functional electrical stimulation (FES) on endothelial
function to that of conventional bicycle training. Eligible patients
were those with New York Heart Association class II or III heart failure
symptoms and ejection fractions <= 0.35. Two physical conditioning
programs were delivered: FES of the muscles of the lower limbs and
bicycle training, each lasting for 6 weeks, with a 6-week washout period
between them. Brachial artery flow-mediated dilation (FMD) and other
parameters were assessed before and after FES and the bicycle training
program. FES resulted in a significant improvement in FMD, which
increased from 5.9 +/- 0.5% to 7.7. +/- 0.5% (95% confidence interval
for the difference 1.5% to 2.3%, p <0.001). Bicycle training also
resulted in a substantial improvement of endothelial function. FMD
increased from 6.2 +/- 0.4% to 9.2 +/- 0.4% (95% confidence interval
for the difference 2.5% to 3.5%, p <0.001). FES was associated with a
41% relative increase in FMD, compared to 57% with bicycle exercise
(95% confidence interval for the difference between the relative
changes 1.2% to 30.5%, p = 0.034). This resulted in attaining a
significantly higher FMD value after bicycle training compared to FES
(9.2 +/- 0.4% vs 7.7 +/- 0.5%, p <0.001). In conclusion, the effect of
muscle FES in patients with heart failure on endothelial function,
although not equivalent to that of conventional exercise, is
substantial. Muscle FES protocols may prove very useful in the treatment
of patients with heart failure who cannot or will not adhere to
conventional exercise programs. (C) 2010 Elsevier Inc. All rights
reserved. (Am J Cardiol 2010;106:1621-1625)
Συγγραφείς:
Deftereos, Spyridon
Giannopoulos, Georgios
Raisakis,
Konstantinos
Kossyvakis, Charalampos
Kaoukis, Andreas
Driva,
Metaxia
Pappas, Loukas
Panagopoulou, Vasiliki
Ntzouvara,
Olga
Karavidas, Apostolos
Pyrgakis, Vlasios
Rentoukas, Ilias
and Aggeli, Constadina
Stefanadis, Christodoulos
Περιοδικό:
AMERICAN JOURNAL OF CARDIOLOGY
Εκδότης:
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI:
10.1016/j.amjcard.2010.07.040
