Τίτλος:
Gender variation of exercise-induced anti-arrhythmic protection: the
Ikaria Study
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Methods: In a cross-sectional survey 1071 inhabitants of Ikaria Island
(65 +/- 13 years, 47% males) were enrolled. PA was estimated by means
of IPAQ classifying the participants into low, moderate and vigorous
group. QT duration was measured from a surface electrocardiogram; while
using Bazett’s formula the heart-rate-corrected QT (QTc) was calculated.
Results: Among participants, 85% reported at least moderate PA levels.
Women in the ‘vigorous’ and ‘moderate’ PA level compared to those in the
‘low’ PA level had significantly shorter QTc (408 +/- 2 ms vs. 411 +/- 1
ms vs. 419 +/- 2 ms, P = 0.001, respectively). In contrast, no
significant difference in QTc according to PA levels was observed in men
(P = 0.053). Linear regression analysis revealed that PA level was
significantly associated with shorter QTc in women after adjustment for
established confounders; while no such association was evident in men.
Furthermore, compared to the ‘low’ PA group, women in the ‘vigorous’ PA
group were 5.5-times less likely to have QTc interval above 450 ms (P =
0.031).
Conclusion: Increased PA is associated with shorter QTc interval only in
middle-aged and elderly women of Ikaria Island irrespectively of
participant’s habits or medical conditions, illustrating gender
differences in the cardioprotective effect of habitual exercise.
Συγγραφείς:
Oikonomou, E.
Chrysohoou, C.
Tsiachris, D.
Vogiatzi, G. and
Gialafos, E.
Marinos, G.
Tsitsinakis, G.
Dimitriadis, K. and
Tousoulis, D.
Pitsavos, C.
Stefanadis, C.
Περιοδικό:
QJM: An International Journal of Medicine
Εκδότης:
Oxford University Press
DOI:
10.1093/qjmed/hcr112
