Τίτλος:
Duloxetine Versus Citalopram and Sertraline in the Treatment of
Poststroke Depression, Anxiety, and Fatigue
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The authors sought to determine the relative efficacy and tolerability
of duloxetine versus citalopram and sertraline in the treatment of
poststroke depression (PSD), anxiety, and fatigue. A group of 60
patients with PSD were assigned to receive duloxetine, citalopram, or
sertraline and were assessed over a 3-month period for depression,
anxiety, and fatigue. Improvement of depression and anxiety, but not
fatigue, was observed in all study groups. Duloxetine was well tolerated
and significantly more effective than citalopram and sertraline for the
treatment of anxiety symptoms in PSD patients. None of the
antidepressants used was effective for reducing symptoms of fatigue.
(The Journal of Neuropsychiatry and Clinical Neurosciences 2012;
24:349-353)
Συγγραφείς:
Karaiskos, Dimitrios
Tzavellas, Elias
Spengos, Konstantinos and
Vassilopoulou, Sofia
Paparrigopoulos, Thomas
Περιοδικό:
Journal of Neuropsychiatry and Clinical Neurosciences
Εκδότης:
AMER PSYCHIATRIC PUBLISHING, INC
DOI:
10.1176/appi.neuropsych.11110325
