Τίτλος:
MicroRNAs in Cardiovascular Therapeutics
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Recent research reveals the crucial role microRNAs (miRNAs) in the
pathogenesis and progression of many pathological conditions, including
cardiovascular diseases. It is widely documented that miRNAs represent
critical regulators of cardiovascular function and participate in almost
all aspects of cardiovascular biology. In particular, they are involved
in several pathophysiological pathways of various manifestations of
cardiovascular disease, such as coronary artery disease, heart failure,
stroke, diabetes mellitus, arterial hypertension and cardiac
arrhythmias. In the present article we review the available literature
regarding to the role of miRNAs in certain cardiovascular conditions.
Moreover, we discuss the therapeutic potential of miRNAs for treating
cardiovascular diseases and we attempt to highlight future directions.
Συγγραφείς:
Siasos, Gerasimos
Tousoulis, Dimitris
Tourikis, Panagiotis and
Mazaris, Savas
Zakynthinos, Giorgos
Oikonomou, Evangelos and
Kokkou, Eleni
Kollia, Christina
Stefanadis, Christodoulos
Περιοδικό:
Current Topics in Medicinal Chemistry
Εκδότης:
BENTHAM SCIENCE PUBL LTD
Λέξεις-κλειδιά:
microRNAs; cardiovascular disease; therapy; atherosclerosis
DOI:
10.2174/15680266113139990109
