Modulation of gut microbiota downregulates the development of food allergy in infancy

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3160057 22 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Modulation of gut microbiota downregulates the development of food
allergy in infancy
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
In humans, microbial colonisation of the intestine begins just after
birth. However, development of the normal flora is a gradual process,
which is initially determined by factors such as genetic aspects, the
maternal-foetal interaction, place and mode of delivery, early feedings
strategies, and the use of antibiotics. Current knowledge on the
significance and impact of the gut microflora on the development of the
gut immune system indicates that a close relationship between allergic
sensitisation and the development of the intestinal microflora may occur
in infancy. Intestinal micro-organisms could downregulate the allergic
inflammation by counterbalancing type 2 T-helper cell responses and by
enhancing allergen exclusion through an immunological response. (C) 2013
SEICAP. Published by Elsevier Espana, S.L. All rights reserved.
Έτος δημοσίευσης:
2014
Συγγραφείς:
Tsabouri, S.
Priftis, K. N.
Chaliasos, N.
Siamopoulou, A.
Περιοδικό:
Allergologia et Immunopathologia
Εκδότης:
Codon Publications
Τόμος:
42
Αριθμός / τεύχος:
1
Σελίδες:
69-77
Λέξεις-κλειδιά:
Food allergy; Microbiota; Infancy
Επίσημο URL (Εκδότης):
DOI:
10.1016/j.aller.2013.03.010
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.