Περίληψη:
This review summarizes the data challenging the concept that
cardiovascular protection through high-density lipoprotein (HDL) is only
associated with its serum concentration. This conventional impression
about its protective role now appears obsolete. New aspects of its
mechanisms are revealed and novel therapeutic strategies are based on
them. However, data from long-term cost-effectiveness studies of
treating HDL are still needed. There is a need for biomarkers that
represent the functional characteristics of HDL in order to better
quantify the total cardiovascular risk. (C) 2015 MedReviews (R), LLC
Συγγραφείς:
Katsi, Vasiliki
Kallistratos, Manolis S.
Pavlidis, Antonios N.
and Karpettas, Nikos
Skoumas, Ioannis
Pavleros, Nikonas and
Manolis, Athanasios J.
Pitsavos, Christos
Tousoulis, Dimitris
and Stefanadis, Christodoulos
Kallikazaros, Ioannis