The Mystery of High-density Lipoprotein: Quantity or Quality? Update on Therapeutic Strategies

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3164014 19 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
The Mystery of High-density Lipoprotein: Quantity or Quality? Update on
Therapeutic Strategies
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
This review summarizes the data challenging the concept that
cardiovascular protection through high-density lipoprotein (HDL) is only
associated with its serum concentration. This conventional impression
about its protective role now appears obsolete. New aspects of its
mechanisms are revealed and novel therapeutic strategies are based on
them. However, data from long-term cost-effectiveness studies of
treating HDL are still needed. There is a need for biomarkers that
represent the functional characteristics of HDL in order to better
quantify the total cardiovascular risk. (C) 2015 MedReviews (R), LLC
Έτος δημοσίευσης:
2015
Συγγραφείς:
Katsi, Vasiliki
Kallistratos, Manolis S.
Pavlidis, Antonios N.
and Karpettas, Nikos
Skoumas, Ioannis
Pavleros, Nikonas and
Manolis, Athanasios J.
Pitsavos, Christos
Tousoulis, Dimitris
and Stefanadis, Christodoulos
Kallikazaros, Ioannis
Περιοδικό:
REVIEWS IN CARDIOVASCULAR MEDICINE
Εκδότης:
IMR Press Limited
Τόμος:
16
Αριθμός / τεύχος:
1
Σελίδες:
9-19
Λέξεις-κλειδιά:
Apolipoprotein A-1; Cardiovascular protection; Dyslipidemia;
High-density lipoprotein; Risk factors
Επίσημο URL (Εκδότης):
DOI:
10.3909/ricm0719
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.