Περίληψη:
Atherosclerosis is the main underlying pathology of cardiovascular
disease and is precipitated by various hereditary and non-hereditary
risk factors. Inflammation is considered an important step in the
progression of atherosclerosis and involves numerous cells, mediators
and cellular procedures. Therefore, a biomarker able to determine the
vascular inflammatory status is imperative as the combination of
inflammatory biomarkers with the classic risk factors might provide
further information about atherosclerosis progression and cardiovascular
risk. The identification of novel inflammatory molecules and the
improvement in analytical methods allows the potential implementation of
these tests in every day clinical practice. In the current article, we
focus on the role of established and novel biomarkers in atherosclerosis
progression and in the determination of cardiovascular risk. We also
present recent data concerning the risk stratification of patients
according to their inflammatory status and the possible
anti-inflammatory treatment strategies.
Συγγραφείς:
Siasos, Gerasimos
Tsigkou, Vicky
Oikonomou, Evangelos and
Zaromitidou, Marina
Tsalamandris, Sotiris
Mourouzis,
Konstantinos
Vavuranakis, Manolis
Anastasiou, Maria
Vlasis,
Konstantinos
Limperi, Maria
Gennimata, Vasiliki
Boletis,
John N.
Papavassiliou, Athanasios G.
Tousoulis, Dimitris
