Τίτλος:
Pandemic influenza A vs seasonal influenza A in hospitalized children in
Athens
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Data on pandemic H1N1 influenza (pH1N1) virus infection in
hospitalised children are limited. Aims and Objectives: To examine the
epidemiological and clinical characteristics of children hospitalised
with pH1N1 at a large tertiary-care centre in Athens and compare them
with those of children hospitalised with seasonal influenza A in
previous years.
Methods: All children (n=146) admitted with confirmed pH1N1 between
October 2009 to February 2010 and January 2011 to May 2011 were
included. Data on children >= 6 months of age (n=109) were compared with
those of 138 children admitted with seasonal influenza A who were
examined during two previous influenza seasons (2002-2003 and
2004-2005).
Results: The age distribution was similar between seasonal and pandemic
H1N1. Bronchial asthma was significantly more common in the seasonal
influenza group but the clinical presentation was similar in the two
groups, except that fever was more common in patients with pH1N1.
Children admitted with seasonal influenza were more likely to develop
acute otitis media. There were no significant differences between the
two groups for severe outcomes (admission to the ICU, mechanical
ventilation or death). Only one child with seasonal influenza (0.6%)
and three with pH1N1 influenza (2%) required admission to the ICU. Mean
length of hospitalisation was longer in the seasonal influenza group.
Conclusion: Clinical manifestations were similar between pH1N1 and
seasonal influenza, and the pandemic virus did not appear to cause more
severe disease in hospitalised children.
Συγγραφείς:
Stripeli, F.
Logotheti, I.
Vraila, V. M.
Balta, C. and
Patsioura, A.
Papaevangelou, V.
Papadatos, I.
Baka, A. and
Tsiodras, S.
Tsolia, M. N.
Περιοδικό:
Paediatrics and International Child Health
Εκδότης:
TAYLOR & FRANCIS LTD LONDON
Λέξεις-κλειδιά:
Children; Hospitalisation; Pandemic H1N1 influenza; Seasonal influenza
DOI:
10.1179/2046905513Y.0000000111
