Persistent Subretinal Fluid After Successful Full-Thickness Macular Hole Surgery: Prognostic Factors, Morphological Features and Implications on Functional Recovery

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3166379 15 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Persistent Subretinal Fluid After Successful Full-Thickness Macular Hole
Surgery: Prognostic Factors, Morphological Features and Implications on
Functional Recovery
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The present study aimed to identify preoperative factors that predispose
the development of subretinal fluid (SRF) following successful macular
hole (MH) surgery.
Thirty-four eyes of 33 consecutive patients that underwent pars plana
vitrectomy for idiopathic full-thickness MH surgery were included in
this retrospective study. Best corrected visual acuity (BCVA), and
spectral domain-optical coherence tomography (OCT) images were evaluated
pre- and postoperatively in all cases. Patient’s demographic
characteristics, stage of MH, measurements of base diameter and minimum
aperture diameter of the MH, preoperative foveal vitreomacular traction
and selected intra-operative parameters were correlated with the
development of postoperative SRF.
Postoperative SRF was observed in 15 cases (48%). Total absorption of
SRF was observed in 73% of affected eyes and was most commonly seen
between the third and the fifth postoperative month. One patient
developed lamellar hole leading to full-thickness MH. Postoperative BCVA
was similar between the eyes that did and the eyes that did not develop
postoperative SRF (0.31 +/- A 0.2 vs 0.35 +/- A 0.2; p a parts per
thousand yen 0.05). Development of postoperative SRF was significantly
associated with the presence of preoperative foveal vitreomacular
traction (p = 0.048), stage II MH (p = 0.017) and smaller size of the
closest distance between the MH edges (p = 0.046).
Postoperative SRF is a common occurrence following successful MH
surgery. Meticulous evaluation of preoperative clinical and OCT findings
may disclose risk factors associated with this condition. Based on our
observations, idiopathic holes of early stage appear to be at a higher
risk of developing postoperative SRF. This could be a point of interest
with the advancing use of enzymatic proteolysis.
Έτος δημοσίευσης:
2015
Συγγραφείς:
Tranos, Paris G.
Stavrakas, Panagiotis
Vakalis, Athanasios N.
and Asteriadis, Solon
Lokovitis, Evangelos
Konstas, Anastasios
G. P.
Περιοδικό:
Advances in Therapy
Εκδότης:
Springer-Verlag
Τόμος:
32
Αριθμός / τεύχος:
7
Σελίδες:
705-714
Λέξεις-κλειδιά:
Full-thickness macular hole; Outer retinal defects; Persistent
subretinal fluid; Prognostic factors; Stage of macular hole; Vitrectomy
Επίσημο URL (Εκδότης):
DOI:
10.1007/s12325-015-0227-z
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