Τίτλος:
Effect of major lifestyle risk factors, independent and jointly, on life
expectancy with and without cardiovascular disease: results from the
Consortium on Health and Ageing Network of Cohorts in Europe and the
United States (CHANCES)
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Seldom have studies taken account of changes in lifestyle habits in the
elderly, or investigated their impact on disease-free life expectancy
(LE) and LE with cardiovascular disease (CVD). Using data on subjects
aged 50+ years from three European cohorts (RCPH, ESTHER and Tromso), we
used multi-state Markov models to calculate the independent and joint
effects of smoking, physical activity, obesity and alcohol consumption
on LE with and without CVD. Men and women aged 50 years who have a
favourable lifestyle (overweight but not obese, light/moderate drinker,
non-smoker and participates in vigorous physical activity) lived between
7.4 (in Tromso men) and 15.7 (in ESTHER women) years longer than those
with an unfavourable lifestyle (overweight but not obese, light/moderate
drinker, smoker and does not participate in physical activity). The
greater part of the extra life years was in terms of “disease-free”
years, though a healthy lifestyle was also associated with extra years
lived after a CVD event. There are sizeable benefits to LE without CVD
and also for survival after CVD onset when people favour a lifestyle
characterized by salutary behaviours. Remaining a non-smoker yielded the
greatest extra years in overall LE, when compared to the effects of
routinely taking physical activity, being overweight but not obese, and
drinking in moderation. The majority of the overall LE benefit is in
disease free years. Therefore, it is important for policy makers and the
public to know that prevention through maintaining a favourable
lifestyle is “never too late”.
Συγγραφείς:
O'Doherty, Mark G.
Cairns, Karen
O'Neill, Vikki
Lamrock,
Felicity
Jorgensen, Torben
Brenner, Hermann
Schoettker, Ben
and Wilsgaard, Tom
Siganos, Galatios
Kuulasmaa, Kari and
Boffetta, Paolo
Trichopoulou, Antonia
Kee, Frank
Περιοδικό:
European Journal of Epidemiology
Λέξεις-κλειδιά:
CHANCES; Ageing; Smoking; Obesity; Cardiovascular disease; Mortality
DOI:
10.1007/s10654-015-0112-8
