Περίληψη:
Various food patterns have been associated with weight change in adults,
but it is unknown which combinations of nutrients may account for such
observations. We investigated associations between main nutrient
patterns and prospective weight change in adults.
This study includes 235,880 participants, 25-70 years old, recruited
between 1992 and 2000 in 10 European countries. Intakes of 23 nutrients
were estimated from country-specific validated dietary questionnaires
using the harmonized EPIC Nutrient DataBase. Four nutrient patterns,
explaining 67 % of the total variance of nutrient intakes, were
previously identified from principal component analysis. Body weight was
measured at recruitment and self-reported 5 years later. The
relationship between nutrient patterns and annual weight change was
examined separately for men and women using linear mixed models with
random effect according to center controlling for confounders.
Mean weight gain was 460 g/year (SD 950) and 420 g/year (SD 940) for men
and women, respectively. The annual differences in weight gain per one
SD increase in the pattern scores were as follows: principal component
(PC) 1, characterized by nutrients from plant food sources, was
inversely associated with weight gain in men (-22 g/year; 95 % CI -33
to -10) and women (-18 g/year; 95 % CI -26 to -11). In contrast, PC4,
characterized by protein, vitamin B2, phosphorus, and calcium, was
associated with a weight gain of +41 g/year (95 % CI +2 to +80) and +88
g/year (95 % CI +36 to +140) in men and women, respectively.
Associations with PC2, a pattern driven by many micro-nutrients, and
with PC3, a pattern driven by vitamin D, were less consistent and/or
non-significant.
We identified two main nutrient patterns that are associated with
moderate but significant long-term differences in weight gain in adults.
Συγγραφείς:
Freisling, Heinz
Pisa, Pedro T.
Ferrari, Pietro
Byrnes,
Graham
Moskal, Aurelie
Dahm, Christina C.
Vergnaud,
Anne-Claire
Boutron-Ruault, Marie-Christine
Fagherazzi, Guy and
Cadeau, Claire
Kuehn, Tilman
Neamat-Allah, Jasmine
Buijsse,
Brian
Boeing, Heiner
Halkjaer, Jytte
Tjonneland, Anne and
Hansen, Camilla P.
Ramon Quiros, J.
Travier, Noemie and
Molina-Montes, Esther
Amiano, Pilar
Huerta, Jose M. and
Barricarte, Aurelio
Khaw, Kay-Tee
Wareham, Nicholas
Key, Tim
J.
Romaguera, Dora
Lu, Yunxia
Lassale, Camille M.
Naska,
Androniki
Orfanos, Philippos
Trichopoulou, Antonia
Masala,
Giovanna
Pala, Valeria
Berrino, Franco
Tumino, Rosario and
Ricceri, Fulvio
de Magistris, Maria Santucci
Bueno-de-Mesquita,
H. Bas
Ocke, Marga C.
Sonestedt, Emily
Ericson, Ulrika and
Johansson, Mattias
Skeie, Guri
Weiderpass, Elisabete and
Braaten, Tonje
Peeters, Petra H. M.
Slimani, Nadia
