Τίτλος:
Effect of carotenoids dietary supplementation on macular function in
diabetic patients
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: Diabetic retinopathy is a major cause of visual impairment
and blindness among working-age people worldwide. The aim of our study
was to investigate the effects of a carotenoid supplementation on
retinal thickness and macular function of patients with diabetes using
optical coherence tomography (OCT) and multifocal electroretinography
(mfERG).
Methods: A retrospective study of one hundred and twenty eyes of sixty
patients age between 40 and 60 years with non-insulin dependent type 2
diabetes mellitus without diabetic retinopathy who underwent OCT and
mfERG and took vitamin supplements for a period of two years. Patients
received a carotenoid supplement containing lutein (10 mg), zeaxanthin
(2 mg) and meso-zeaxanthin (10 mg) once a day for two years. The
thickness of the fovea was evaluated using OCT and the macular function
was tested by mfERG.
Results: OCT showed an increase in the central foveal thickness and
mfERG revealed increased retinal response density within the central 13
degrees surrounding the fovea (rings 1 to 3) at two years after the
onset of carotenoids supplement intake.
Conclusion: The use of carotenoid supplements may be of benefit for
improving visual function of type 2 diabetes patients. However, further
study is needed to assess the treatment's long-term efficacy.
Συγγραφείς:
Moschos, Marilita M.
Dettoraki, Maria
Tsatsos, Michael and
Kitsos, George
Kalogeropoulos, Christos
Περιοδικό:
Eye and Vision
Λέξεις-κλειδιά:
Carotenoids; Diabetes mellitus; Visual function; Multifocal
electroretinography; Optical coherence tomography
DOI:
10.1186/s40662-017-0088-4
