Περίληψη:
We describe histologically cases of patients between 31 and 60 years of
age who had fibromuscular dysplasia (FMD) in the tunica media (TM) of
the left ventricle papillary muscles (PM) arteries. We also compared
them with our previous findings in subjects younger than 30 years of
age. We examined histologically samples taken from the tip of the
anterior PM of the left ventricle in 200 healthy male hearts. In 33
cases (16.5 %), FMD was in the TM. We divided these cases into three
subgroups (A, B, C) based on the degree of replacement of smooth muscle
cells by fibrous tissue, and thus identified 17, 11 and 5 cases,
respectively. Until the age of 41, the typical lesions were often
localized within the TM. Beyond that age, the fibrous tissue increased
in the TM wall and in the surrounding area of the vessels, causing
dysfunction of the PM. Degenerative lesions, as well as inflammatory
infiltration, were found after the age of 53. The findings of this study
will be useful to cardiologists and cardiac surgeons, in pointing out
that, after the age of 44 years old, some PM and their supporting valves
may present a degree of dysfunction.
Συγγραφείς:
Nerantzis, Christos E.
Karakoukis, Nikolaos G.
Di Lernia, George
C.
Bouzianis, Sotirios G.
Sakelaris, Nikolaos G.
Agapitos,
Emmanouil B.
