A novel Hemi-Body Irradiation technique using electron beams (HBIe(-))

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3178723 31 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
A novel Hemi-Body Irradiation technique using electron beams (HBIe(-))
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: Certain radiation responsive skin diseases may develop symptoms
on the upper or the lower half of the body. The concept of a novel
Hemi-Body Electron Irradiation (HBIe(-)) technique, described in this
work, provides a low cost, LINAC based, intermediate treatment option in
between extremely localized and Total Skin irradiation techniques.
Materials and methods: The HBIe(-) technique, developed in our
department, incorporates a custom crafted treatment chamber equipped
with adjustable Pb shielding and a single electron beam in extended
Source-Skin Distance (SSD) setup. The patient is positioned in
‘Stanford’ technique positions. The geometrical setup provides both
optimal dose homogeneity and dose deposition up to a depth of 2 cm. To
confirm this, the following characteristics were measured and evaluated:
a) percentage depth dose (PDD) on the treatment plane produced by a
single electron beam at perpendicular incidence for six fields at
‘Stanford’ angles, b) 2D profile of the entrance dose on the treatment
plane produced by a single field and c) the total surface dose on an
anthropomorphic phantom delivered by all 6 fields.
Results: The resulting homogeneity of the surface dose in the treatment
plane for an average patient was 5-6%, while surface dose homogeneity
on the anthropomorphic phantom was 7% for both the upper and the lower
HBIe(-) variants. The total PDD exhibits an almost linear decrease to a
practical range of 2 g/cm(2).
Conclusion: In conclusion, HBIe(-) was proven effective in delivering
the prescribed dose to the target area, while protecting the healthy
skin.
Έτος δημοσίευσης:
2018
Συγγραφείς:
Delinikolas, Panagiotis
Patatoukas, Georgios
Kouloulias,
Vasilios
Dilvoi, Maria
Plousi, Agapi
Efstathopoulos,
Efstathios
Platoni, Kalliopi
Περιοδικό:
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
Εκδότης:
Elsevier Sci Ltd, Exeter, United Kingdom
Τόμος:
46
Σελίδες:
16-24
Λέξεις-κλειδιά:
Half-body skin irradiation; Stanford technique; Kaposi's sarcoma; T-cell
lymphoma
Επίσημο URL (Εκδότης):
DOI:
10.1016/j.ejmp.2017.12.022
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.