Τίτλος:
A rare case of advanced lung cancer presenting as a symptomatic gastric
tumor
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Although gastric metastases have been estimated to occur in less than
2% of cancer patients, an increased use of upper digestive tract
endoscopy allows for a higher detection of secondary gastric tumors. We
describe the case of a 66-year-old male patient presenting with mild
pain in the sternum and upper abdominal area. Physical examination
revealed a right parietal skull tumor, with no other significant
clinical changes. Upon exclusion of an acute coronary syndrome, upper
digestive tract endoscopy was performed, showing the presence of an
ulcerated tumor located in the gastric fundus. Histopathologic
examination of the biopsy sample and immunohistochemical tests suggested
a pulmonary origin of the gastric tumor. Whole body computer tomography
showed the presence of tumors in the gastric fundus, left lung, liver,
kidneys, bones and brain. Transbronchial biopsy of the lung tumor
certified the diagnosis of non-small cell lung cancer, with the same
immunohistochemical profile as the gastric tumor. Hence, it was
considered the origin of the metastases. Biopsy of the skull tumor also
had the identical tumor histology. Whole brain radiotherapy was
performed for the brain metastases and subsequent chemotherapy was
administered. Although non-specific, gastrointestinal signs and symptoms
occurring in lung cancer patients should alert the clinicians as to the
possibility of gastrointestinal metastases and prompt endoscopic
evaluation.
Συγγραφείς:
Nitipir, Cornelia
Ginghina, Octav
Popa, Liliana
Andrei,
Florin
Tudor, Nicolaie
Radu, Irina
Iaciu, Cristian and
Orlov, Cristina
Vasilescu, Florina
Balalau, Cristian
Leon,
Grigoris
Negrei, Carolina
Barbu, Maria Alexandra
Περιοδικό:
Molecular and Clinical Oncology
Εκδότης:
SPANDIDOS PUBL LTD
Λέξεις-κλειδιά:
immunohistochemistry; gastric metastases; non-small cell lung cancer
DOI:
10.3892/mco.2018.1565
