Τίτλος:
Novel approaches for the treatment of ventricular tachycardia
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Ventricular tachycardia (VT) is a crucial cause of sudden cardiac death
(SCD) and a primary cause of mortality and morbidity in patients with
structural cardiac disease. VT includes clinical disorders varying from
benign to life-threatening. Most life-threatening episodes are
correlated with coronary artery disease, but the risk of SCD varies in
certain populations, with various underlying heart conditions, specific
family history, and genetic variants. The targets of VT management are
symptom alleviation, improved quality of life, reduced implantable
cardioverter defibrillator shocks, prevention of reduction of left
ventricular function, reduced risk of SCD, and improved overall
survival. Antiarrhythmic drug therapy and endocardial catheter ablation
remains the cornerstone of guideline-endorsed VT treatment strategies in
patients with structural cardiac abnormalities. Novel strategies such as
epicardial ablation, surgical cryoablation, transcoronary alcohol
ablation, pre-procedural imaging, and stereotactic ablative radiotherapy
are an appealing area of research. In this review, we gathered all
recent advances in innovative therapies as well as experimental evidence
focusing on different aspects of VT treatment that could be significant
for future favorable clinical applications.
Συγγραφείς:
Spartalis, Michael
Spartalis, Eleftherios
Tzatzaki, Eleni and
Tsilimigras, Diamantis I.
Moris, Demetrios
Kontogiannis,
Christos
Livanis, Efthimios
Iliopoulos, Dimitrios C. and
Voudris, Vassilis
Theodorakis, George N.
Περιοδικό:
WORLD JOURNAL OF CARDIOLOGY
Εκδότης:
BAISHIDENG PUBLISHING GROUP INC
Λέξεις-κλειδιά:
Ventricular tachycardia; Catheter ablation; Epicardial; Sudden cardiac
death; Novel techniques; Substrate
DOI:
10.4330/wjc.v10.i7.52
