Τίτλος:
The Goodness-of-fit of the Fractal Dimension as a Diagnostic Factor in
Breast cancer
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A large number of studies have found that the fractal dimension
increases with the progression towards pathological or more pathological
states, but there are also studies that have demonstrated the opposite
relationship. In this study, we calculate the nuclear box-counting
fractal dimension of 109 malignant, 113 benign, and 80 normal isolated
breast cells in order to investigate its possible diagnostic importance.
We computed the fractal dimension and its goodness-of-fit (i.e., the
r-squared value that describes how well the regression line fits the set
of the measurements) for two different sets of box size lengths. The
statistical analysis did not confirm an important diagnostic potential
of the nuclear fractal dimension of isolated breast cells. However, the
goodness-of-fit did display a diagnostic potential. The r-squared value
may be able to serve as a complementary diagnostic parameter.
Συγγραφείς:
Maipas, Sotirios
Nonni, Afroditi
Politi, Ekaterini
Sarlanis,
Helen
Kavantzas, Nikolaos G.
Λέξεις-κλειδιά:
fractal dimension; box-counting dimension; goodness-of-fit; breast
cancer; cancer diagnosis
