Περίληψη:
Objective Methods Our aim was to evaluate the Paris System for reporting
urinary cytology, especially in the field of atypia. During the last
year, 104 urinary cases had atypical cytology. These cases were reviewed
and reclassified by three cytopathologists using the Paris criteria.
Cyto-histological correlation was performed in 47 cases. Additionally,
all cytology diagnoses were correlated with double immunocytochemistry
for p53 and CK20 result. Interobserver consistency was also evaluated.
Results Conclusions Out of 104 atypical cases, 30 were classified as
benign, 49 atypical and 25 suspicious for high-grade urothelial
carcinoma (HGUC). Diagnostic consistency between the three observers
reached 93.27%. Using the new criteria, only 47.1% of the cases
remained in the atypical category. The rate of HGUC histology was
14.3%, 26.7% and 96% in the benign, atypical and suspicious for HGUC
cytological categories, respectively. Immunocytochemistry positivity was
observed in 25.9%, 41.8% and 80% of the cases in the three diagnostic
groups. The Paris System for reporting urinary cytology provides clear,
easy to adopt criteria, which lead to diagnostic categories with
clinical significance, facilitating patient management decisions.
Συγγραφείς:
Mikou, P.
Lenos, M.
Papaioannou, D.
Vrettou, K.
Trigka,
E-A.
Sousouris, S.
Constantinides, C.
