Περίληψη:
Introduction: There are appreciable concerns among European health
authorities with growing expenditure on cancer medicines and issues of
sustainability. The enhanced use of low-cost generics could help.
Aims: Consequently, there is a need to comprehensively document current
and future arrangements regarding the pricing of generic cancer
medicines across Europe, and whether these are indication specific, as
well as how this translates into actual prices to provide future
direction.
Methodology: Mixed-method approach with qualitative research among
senior health authority personnel and their advisers. Quantitative
research via health authority databases to ascertain current prices for
oral cancer medicines that had lost their patent and the influence of
population size and economics on prices.
Results: Twenty-five European countries participated. The research found
the following issues: (a) variable approaches to the pricing of generic
cancer medicines, which will continue; (b) no concerns with substitution
for oral generic cancer medicines; (c) substantial price reductions
versus originators for generic capecitabine (up to -93.1%), generic
imatinib (up to -97.8%) and generic temozolomide (up to -80.7%).
Prices for oncology medicines are not generally indication specific, and
are not affected by population size although influenced by pricing
approaches. There have also been price increases for some non-patented
cancer medicines following manufacturer changes although now
stabilizing.
Conclusion: The considerable price reductions seen for some generics
means health authorities should further encourage the use of generic
oncology medicines when they become available to fund increased volumes
and new valued cancer medicines. Countries are also starting to address
price increases for generics following changes in the manufacturer.
Συγγραφείς:
Godman, Brian
Hill, Andrew
Simoens, Professor Steven
Kurdi,
Amanj
Gulbinovic, Jolanta
Martin, Antony P.
Timoney, Angela
and Gotham, Dzintars
Wale, Janet
Bochenek, Tomasz
Rothe,
Celia C.
Hoxha, Iris
Malaj, Admir
Hierlaender, Christian and
Sauermann, Robert
Hamelinck, Wouter
Mitkova, Zornitsa and
Petrova, Guenka
Laius, Ott
Sermet, Catherine
Langer, Irene
and Selke, Gisbert W.
Yfantopoulos, John
Joppi, Roberta and
Jakupi, Arianit
Poplavska, Elita
Greiciute-Kuprijanov, Ieva and
Bonanno, Patricia Vella
Piepenbrink, J. F. (Hans)
de Valk,
Vincent
Hagen, Carolin
Ringerud, Anne Marthe
Plisko, Robert
and Wladysiuk, Magdalene
Markovic-Pekovic, Vanda
Grubisa, Natasa
and Ponorac, Tatjana
Mardare, Ileana
Novakovic, Tanja and
Parker, Mark
Furst, Jurij
Tomek, Dominik
Cortadellas, Merce
Obach
Zara, Corinne
Juhasz-Haverinen, Maria
Skiold, Peter
and McTaggart, Stuart
Haycox, Alan
