Τίτλος:
Vigabatrin-Induced Encephalopathy in a 5.5-Month-Old Girl with Infantile
Spasms due to Tuberous Sclerosis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A 5.5-month-old female infant with tuberous sclerosis complex presented
with infantile spasms and was treated with vigabatrin. As her condition
did not improve, she was given adrenocorticotropic hormone (ACTH)
intramuscularly which stopped the spasms and improved the
electroencephalogram (EEG) abnormalities. However, she developed
encephalopathy with apathy, drowsiness, and generalized slowing in the
EEG. Discontinuation of vigabatrin quickly improved her symptoms and
reversed the EEG slowing. A high index of suspicion is required in order
to diagnose vigabatrin-induced encephalopathy, especially as the
underlying disorders of these patients can be erroneously considered the
cause of the observed encephalopathy.
Συγγραφείς:
Klinaki, Eleni
Argyri, Ioanna
Amountza, Georgia
Ioannidou,
Gerina
Maritsi, Despoina
Garoufi, Anastasia
Vartzelis,
George
Περιοδικό:
Case Reports In Pediatrics
DOI:
10.1155/2019/7249237
