Τίτλος:
Cardiac Magnetic Resonance versus Single-Photon Emission Computed
Tomography for Detecting Coronary Artery Disease and Myocardial
Ischemia: Comparison with Coronary Angiography
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: This study aimed to compare the diagnostic accuracy of
stress single-photon emission computed tomography (SPECT) and stress
cardiac magnetic resonance (CMR) for the assessment of coronary artery
disease (CAD) in the same patients, using coronary angiography as the
reference standard. Methods: Thirty patients with known or suspected CAD
who were referred for exercise SPECT myocardial perfusion imaging (MPI)
for the evaluation of myocardial ischemia underwent stress CMR MPI and
computed tomography coronary angiography (CTCA) or selective coronary
angiography (SCA). The data from the two stress modalities were compared
against the data from angiography. Results: In our study population,
30% of the recruited subjects had significant CAD. The CMR sensitivity
for the detection of significant CAD and/or myocardial ischemia was 89%
and specificity was 76%. For SPECT, the corresponding sensitivity was
78% and specificity was 52%. The negative predictive value was 92%
for CMR and 83% for SPECT. The receiver-operating characteristic (ROC)
analysis evaluating the presence of significant CAD, CMR (area under the
curve (AUC) 0.78) outperformed SPECT (AUC 0.59) (p < 0.01). The ROC
analysis evaluating the presence of myocardial ischemia was also in
favor of CMR (AUC 0.82) versus SPECT (AUC 0.67) (p < 0.01). Conclusions:
CMR has high diagnostic accuracy for the detection of CAD and
stress-induced ischemia and appears to outperform SPECT. CMR may thus be
the preferred noninvasive imaging modality to assess patients with known
or suspected CAD.
Συγγραφείς:
Laspas, Fotios
Pipikos, Theodoros
Karatzis, Emmanouil and
Georgakopoulos, Nikolaos
Prassopoulos, Vasileios
Andreou, John
and Moulopoulos, Lia A.
Chatziioannou, Achilleas
Danias, Peter
G.
Περιοδικό:
DIAGNOSTIC ONCOLOGY
Λέξεις-κλειδιά:
coronary artery disease; single-photon emission computed tomography;
cardiac magnetic resonance; myocardial perfusion
DOI:
10.3390/diagnostics10040190
