Τίτλος:
Vitrectomy for the removal of idiopathic epiretinal membrane with or
without internal limiting membrane peeling: a meta-analysis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: The aim of this study is to analyze the effect of internal
limiting membrane peeling in removal of idiopathic epiretinal membranes
through meta-analysis.
Methods: We searched PubMed for studies published until 30 April 2018.
Inclusion criteria included cases of idiopathic epiretinal membranes,
treated with vitrectomy with or without internal limiting membrane
peeling. Exclusion criteria consisted of coexisting retinal pathologies
and use of indocyanine green to stain the internal limiting membrane.
Sixteen studies were included in our meta-analysis. We compared the
results of surgical removal of epiretinal membrane, with or without
internal limiting membrane peeling, in terms of best-corrected visual
acuity and anatomical restoration of the macula (central foveal
thickness). Studies or subgroups of patients who had indocyanine green
used as an internal limiting membrane stain were excluded from the
study, due to evidence of its toxicity to the retina.
Results: Regarding best-corrected visual acuity levels, the overall mean
difference was -0.29 (95% confidence interval: -0.319 to -0.261), while
for patients with internal limiting membrane peeling was -0.289 (95%
confidence interval: -0.334 to -0.244) and for patients without internal
limiting membrane peeling was -0.282 (95% confidence interval: -0.34 to
-0.225). Regarding central foveal thickness levels, the overall mean
difference was -117.22 (95% confidence interval: -136.70 to -97.74),
while for patients with internal limiting membrane peeling was -121.08
(95% confidence interval: -151.12 to -91.03) and for patients without
internal limiting membrane peeling was -105.34 (95% confidence
interval: -119.47 to -96.21).
Conclusion: Vitrectomy for the removal of epiretinal membrane combined
with internal limiting membrane peeling is an effective method for the
treatment of patients with idiopathic epiretinal membrane.
Συγγραφείς:
Christodoulou, Eleni
Batsos, Georgios
Galanis, Petros and
Kalogeropoulos, Christos
Katsanos, Andreas
Alamanos, Yannis and
Stefaniotou, Maria
Περιοδικό:
THERAPEUTIC ADVANCES IN OPHTHALMOLOGY
Εκδότης:
SAGE Publications Ltd
Λέξεις-κλειδιά:
epiretinal membrane; internal limiting membrane; macular pucker; peeling
DOI:
10.1177/2515841420927133
