Περίληψη:
Purpose The craniometrics of head circumference (HC) and ventricular
size are part of the clinical assessment of infants with hydrocephalus
and are often utilized in conjunction with other clinical and
radiological parameters to determine the success of treatment. We aimed
to assess the effect of endoscopic third ventriculostomy (ETV) and
shunting on craniometric measurements during the follow-up of a cohort
of infants with symptomatic triventricular hydrocephalus secondary to
aqueductal stenosis. Methods We performed a post hoc analysis of data
from the International Infant Hydrocephalus Study (IIHS)-a prospective,
multicenter study of infants (< 24 months old) with hydrocephalus from
aqueductal stenosis who were treated with either an ETV or shunt. During
various stages of a 5-year follow-up period, the following craniometrics
were measured: HC, HC centile, HCz-score, and frontal-occipital horn
ratio (FOR). Data were compared in an analysis of covariance, adjusting
for baseline variables including age at surgery and sex. Results Of 158
enrolled patients, 115 underwent an ETV, while 43 received a shunt. Both
procedures led to improvements in the mean HC centile position
andz-score, a trend which continued until the 5-year assessment point. A
similar trend was noted for FOR which was measured at 12 months and 3
years following initial treatment. Although the values were consistently
higher for ETV compared with shunt, the differences in HC value,
centile, andz-score were not significant. ETV was associated with a
significantly higher FOR compared with shunting at 12 months (0.52 vs
0.44;p = 0.002) and 3 years (0.46 vs 0.38;p = 0.03) of follow-up.
Conclusion ETV and shunting led to improvements in HC centile,z-score,
and FOR measurements during long-term follow-up of infants with
hydrocephalus secondary to aqueductal stenosis. Head size did not
significantly differ between the treatment groups during follow-up,
however ventricle size was greater in those undergoing ETV when measured
at 1 and 3 years following treatment.
Συγγραφείς:
Coulter, Ian C.
Kulkarni, Abhaya V.
Sgouros, Spyros and
Constantini, Shlomi
Constantini, Shlomi
Sgouros, Spyros and
Kulkarni, Abhaya V.
Leitner, Yael
Kestle, John R. W. and
Cochrane, Douglas D.
Choux, Maurice
Gjerris, Fleming
Sherer,
Adina
Akalan, Nejat
Bilginer, Burcak
Navarro, Ramon and
Vujotic, Ljiljana
Haberl, Hannes
Thomale, Ulrich-Wilhelm and
Zuccaro, Graciela
Jaimovitch, Roberto
Frim, David
Loftis,
Lori
Swift, Dale M.
Robertson, Brian
Gargan, Lynn and
Bognar, Laszlo
Novak, Laszlo
Cseke, Georgina
Cama, Armando
and Ravegnani, Giuseppe Marcello
Preuss, Matthias
Schroeder,
Henry W.
Fritsch, Michael
Baldauf, Joerg
Mandera, Marek and
Luszawski, Jerzy
Skorupka, Patrycja
Mallucci, Conor and
Williams, Dawn
Zakrzewski, Krzysztof
Nowoslawska, Emilia and
Srivastava, Chhitij
Mahapatra, Ashok K.
Kumar, Raj
Sahu,
Rabi Narayan
Melikian, Armen G.
Korshunov, Anton
Galstyan,
Anna
Suri, Ashish
Gupta, Deepak
Grotenhuis, J. Andre
van
Lindert, Erik J.
da Costa Val, Jose Aloysio
Di Rocco, Concezio
and Tamburrini, Gianpiero
Zymberg, Samuel Tau
Cavalheiro, Sergio
and Jie, Ma
Feng, Jiang
Friedman, Orna
Rajmohamed, Naheeda
and Roszkowski, Marcin
Barszcz, Slawomir
Jallo, George and
Pincus, David W.
Richter, Bridget
Mehdorn, H. M.
Schultka,
Susan
de Ribaupierre, Sandrine
Thompson, Dominic
Gatscher,
Silvia
Wagner, Wolfgang
Koch, Dorothee
Cipri, Saverio and
Zaccone, Claudio
McDonald, Patrick
Int Infant Hydrocephalus
Study
