Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3220137 41 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective: Endourological treatment is assoSummary ciated with a risk of postoperative febrile urinary tract infections and sepsis. The aim of this study was to review the reported rate of infectious complications in relation to the type and modality of the endourologic procedure. Methods: This systematic review was conducted in accordance with the PRISMA guidelines. Two electronic databases (PubMed and EMBASE) were searched. Out of 243 articles retrieved we included 49 studies after full-text evaluation. Results: Random-effects meta-analysis demonstrated that retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PCNL) were associated with not significantly different odds of getting fever (OR = 1.54, 95% CI: 0.99 to 2.39; p = 0.06) or sepsis (OR = 1.52, 95% CI: 0.37 to 6.20, p = 0.56). The odds of getting fever were not significantly different for mini PCNL compared to standard PCNL (OR = 1.11, 95% CI: 0.85 to 1.44; p = 0.45) and for tubeless PCNL compared to standard PCNL (OR = 1.34 95% CI: 0.61 to 2.91, p = 0.47). However, the odds for fever after PCNL with suctioning sheath were lower than the corresponding odds for standard PCNL (OR = 0.37, 95% CI: 0.20 to 0.70, p = 0.002). The odds of getting fever after PCNL with perioperative prophylaxis were not different from the corresponding odds after PCNL with perioperative prophylaxis plus a short oral antibiotic course (before or after the procedure) (OR = 1.31, 95% CI: 0.71 to 2.39, p = 0.38). Conclusions: The type of endourological procedure does not appear to be decisive in the onset of infectious complications, although the prevention of high intrarenal pressure during the procedure could be crucial in defining the risk of infectious complications. © 2022 Edizioni Scripta Manent s.n.c.. All rights reserved.
Έτος δημοσίευσης:
2022
Συγγραφείς:
Bapir, R.
Bhatti, K.H.
Eliwa, A.
García-Perdomo, H.A.
Gherabi, N.
Hennessey, D.
Mourmouris, P.
Ouattara, A.
Perletti, G.
Philipraj, J.
Trinchieri, A.
Buchholz, N.
Περιοδικό:
ARCHIVIO ITALIANO DI UROLOGIA E ANDROLOGIA
Εκδότης:
Page Press Publications
Τόμος:
94
Αριθμός / τεύχος:
1
Σελίδες:
97-106
Λέξεις-κλειδιά:
adverse event; human; length of stay; meta analysis; nephrolithiasis; percutaneous nephrolithotomy; procedures; randomized controlled trial (topic); treatment outcome, Humans; Kidney Calculi; Length of Stay; Nephrolithotomy, Percutaneous; Randomized Controlled Trials as Topic; Treatment Outcome
Επίσημο URL (Εκδότης):
DOI:
10.4081/aiua.2022.1.97
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