Περίληψη:
Knowledge on risk predictors of incident heart failure (HF) in patients with type 2 diabetes (T2D) is crucial given the frequent coexistence of the two conditions and the fact that T2D doubles the risk of incident HF. In addition, HF is increasingly being recognized as an important endpoint in trials in T2D. On the other hand, the diagnostic and prognostic performance of established cardiovascular biomarkers may be modified by the presence of T2D. The present position paper, derived by an expert panel workshop organized by the Heart Failure Association of the European Society of Cardiology, summarizes the current knowledge and gaps in evidence regarding the use of a series of different biomarkers, reflecting various pathogenic pathways, for the prediction of incident HF and cardiovascular events in patients with T2D and in those with established HF and T2D. © 2022 European Society of Cardiology.
Συγγραφείς:
Seferović, P.
Farmakis, D.
Bayes-Genis, A.
Gal, T.B.
Böhm, M.
Chioncel, O.
Ferrari, R.
Filippatos, G.
Hill, L.
Jankowska, E.
Lainscak, M.
Lopatin, Y.
Lund, L.H.
Mebazaa, A.
Metra, M.
Moura, B.
Rosano, G.
Thum, T.
Voors, A.
Coats, A.J.S.
Λέξεις-κλειδιά:
amino terminal pro brain natriuretic peptide; brain natriuretic peptide; natriuretic factor; proadrenomedullin; biological marker, Article; attitude to health; cardiovascular disease; cell function; clinical practice; disease duration; endothelium cell; evidence based practice; glycemic control; health survey; heart failure; heart failure with preserved ejection fraction; heart failure with reduced ejection fraction; human; incidence; inflammation; kidney failure; non insulin dependent diabetes mellitus; oxidative stress; pathogenicity; pathophysiology; prediction; cardiology; complication; heart failure; non insulin dependent diabetes mellitus, Biomarkers; Cardiology; Diabetes Mellitus, Type 2; Heart Failure; Humans
