Τίτλος:
Radical transformations of nucleosides with (Me3Si)3SiH. Generation of a C-1' radical through 1,2-migration of an acyloxy group
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A number of nucleoside substrates has been reduced under free radical conditions with tris(trimethylsilyl)silane. In one case a novel type of a $\beta$-(acyloxy)alkyl radical rearrangement has been observed, which leads through the generation of a C-1' radical species to the stereoselective preparation of an $\alpha$-ribonucleoside. The rate of the above 1,2-migration has been estimated, and a comparison with previously reported results has been made.
Συγγραφείς:
T. Gimisis
G. Ialongo
M. Zamboni
C. Chatgilialoglu
Περιοδικό:
TETRAHEDRON LETTERS
Κύρια θεματική κατηγορία:
Θετικές Επιστήμες
DOI:
10.1016/00404-0399(50)1340-n