Τίτλος:
Carbohydrate restriction in the morning increases weight loss effect of a hypocaloric Mediterranean type diet: a randomized, parallel group dietary intervention in overweight and obese subjects
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective: The aim of this study was to examine the effect of carbohydrate restriction in the morning in the framework of a hypocaloric Mediterranean diet on weight loss and metabolic parameters. Methods: Seventy overweight/obese individuals were randomized to two hypocaloric dietary regimens: one Mediterranean diet (Med-D) and one morning carbohydrate-restriction diet (MCR-D). Participants assigned to the MCR-D were permitted to consume a breakfast low in carbohydrate content, whereas typical Mediterranean morning meals were allowed in the Med-D group. Both diets were identical from midday on. Participants were followed over a period of 2 mo. Results: Individuals in both groups achieved significant reductions in body weight, body mass index, waist circumference, and body fat mass. These reductions were more pronounced in the MCR-D than in the Med-D group (all P < 0.001). More participants in the MCR-D group achieved loss of 5% to 10% of body weight by the end of the first month, as well as 5% to 10% and >10% of body weight by the end of the second month (all P < 0.001). All participants achieved loss of ≥5% baseline body weight by the end of the intervention. Both groups achieved similar reductions in fasting serum glucose, glycated hemoglobin, and serum triacylglycerols as well as improvement in insulin sensitivity. Individuals in the Med-D group showed reductions in total and low-density lipoprotein cholesterol, whereas no such effect was observed in the MCR-D group. Conclusions: Integration of morning carbohydrate restriction into a Mediterranean-type hypocaloric diet resulted in greater weight loss while retaining metabolic benefits in glycemia-related parameters. © 2019 Elsevier Inc.
Συγγραφείς:
Dellis, D.
Tsilingiris, D.
Eleftheriadou, I.
Tentolouris, A.
Sfikakis, P.P., Jr
Dellis, G.
Karanasiou, M.
Meimari, A.
Dimosthenopoulos, C.
Lazarou, S.
Tentolouris, N.
Περιοδικό:
Frontiers in Nutrition
Εκδότης:
ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
Λέξεις-κλειδιά:
glucose; glycosylated hemoglobin; low density lipoprotein cholesterol; triacylglycerol; low density lipoprotein cholesterol; triacylglycerol, adult; Article; body fat; body mass; body weight loss; carbohydrate analysis; carbohydrate intake; clinical effectiveness; controlled study; diet restriction; fat mass; female; food intake; glucose blood level; human; insulin sensitivity; low calorie diet; major clinical study; male; meal; Mediterranean diet; obesity; outcome assessment; patient safety; priority journal; therapy effect; triacylglycerol blood level; waist circumference; administration and dosage; blood; body weight loss; caloric restriction; carbohydrate diet; complication; diet restriction; low calorie diet; low carbohydrate diet; meal; middle aged; non insulin dependent diabetes mellitus; obesity; procedures; prospective study; randomized controlled trial; treatment outcome, Adult; Blood Glucose; Body Mass Index; Breakfast; Caloric Restriction; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Diet, Mediterranean; Diet, Reducing; Dietary Carbohydrates; Fasting; Female; Humans; Male; Middle Aged; Obesity; Overweight; Prospective Studies; Treatment Outcome; Triglycerides; Weight Loss
DOI:
10.1016/j.nut.2019.110578
