Τίτλος:
Fruit and vegetable intake and risk of incident of type 2 diabetes: Results from the consortium on health and ageing network of cohorts in Europe and the United States (CHANCES)
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background/objectives:There is limited information to support definitive recommendations concerning the role of diet in the development of type 2 Diabetes mellitus (T2DM). The results of the latest meta-analyses suggest that an increased consumption of green leafy vegetables may reduce the incidence of diabetes, with either no association or weak associations demonstrated for total fruit and vegetable intake. Few studies have, however, focused on older subjects.Subjects/methods:The relationship between T2DM and fruit and vegetable intake was investigated using data from the NIH-AARP study and the EPIC Elderly study. All participants below the age of 50 and/or with a history of cancer, diabetes or coronary heart disease were excluded from the analysis. Multivariate logistic regression analysis was used to calculate the odds ratio of T2DM comparing the highest with the lowest estimated portions of fruit, vegetable, green leafy vegetables and cabbage intake.Results:Comparing people with the highest and lowest estimated portions of fruit, vegetable or green leafy vegetable intake indicated no association with the risk of T2DM. However, although the pooled OR across all studies showed no effect overall, there was significant heterogeneity across cohorts and independent results from the NIH-AARP study showed that fruit and green leafy vegetable intake was associated with a reduced risk of T2DM OR 0.95 (95% CI 0.91,0.99) and OR 0.87 (95% CI 0.87,0.90) respectively.Conclusions:Fruit and vegetable intake was not shown to be related to incident T2DM in older subjects. Summary analysis also found no associations between green leafy vegetable and cabbage intake and the onset of T2DM. Future dietary pattern studies may shed light on the origin of the heterogeneity across populations. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
Συγγραφείς:
Mamluk, L.
O'Doherty, M.G.
Orfanos, P.
Saitakis, G.
Woodside, J.V.
Liao, L.M.
Sinha, R.
Boffetta, P.
Trichopoulou, A.
Kee, F.
Περιοδικό:
European Journal of Clinical Nutrition
Εκδότης:
Nature Publishing Group
Λέξεις-κλειδιά:
adult; aged; aging; Article; cabbage; cardiometabolic risk; cohort analysis; controlled study; female; food intake; fruit; human; leafy vegetable; male; non insulin dependent diabetes mellitus; prospective study; risk reduction; vegetable; eating; Europe; incidence; middle aged; multivariate analysis; non insulin dependent diabetes mellitus; odds ratio; physiology; risk factor; statistical model; United States, Aged; Diabetes Mellitus, Type 2; Eating; Europe; Female; Fruit; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prospective Studies; Risk Factors; United States; Vegetables
DOI:
10.1038/ejcn.2016.143
