Τίτλος:
HLA-B27 frequency in Greek patients with acute anterior uveitis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The histocompatibility antigen HLA-B27 was identified in 12 out of 33 patients with acute non-granulomatous anterior uveitis. This is a frequency of 36·36%, compared with 4·72% in controls. Seven patients had in addition evidence of systemic disease, including ankylosing spondylitis, sacroiliitis, Reiter's disease, Still's disease, and rheumatoid arthritis. Five of these were HLA-B27 positive, which suggests that the uveitis in many of these cases has a similar aetiology to the uveitis in those with rheumatic disease. It appears that the more severe cases of acute anterior uveitis are related more frequently to the presence of HLA-B27.
Συγγραφείς:
Zervas, J.
Tsokos, G.
Papadakis, G.
Kabouklis, E.
Papadopoulos, D.
Περιοδικό:
British Journal of Ophthalmology
Εκδότης:
BMJ Publishing Group
Λέξεις-κλειδιά:
HLA antigen, acute disease; adult; article; comparative study; female; genetics; Greece; human; immunology; iridocyclitis; male; Reiter syndrome; rheumatoid arthritis; sex difference, Acute Disease; Adult; Arthritis, Rheumatoid; Comparative Study; Female; Greece; HLA Antigens; Human; Male; Middle Age; Reiter Disease; Sex Factors; Uveitis, Anterior
DOI:
10.1136/bjo.61.11.699
