Τίτλος:
Genes, brain dynamics and art: the genetic underpinnings of creativity in dancing, musicality and visual arts
Περίληψη:
Creativity, art and artistic creation in music, dance and visual arts are brain activities specific to humans. Their genetic background remained unexplored for years, but many recent studies have uncovered significant associations with cognition-related genes and loci. These studies are summarized in the present article. Creativity is a trait with heavy genetic influences, which are also associated with mental disorders and altruism. Associated genes include dopaminergic, serotoninergic and other genes (a1-antitrypsin, neuregulin, Brain-derived neurotrophic factor). Music is another complex phenotype with important genetic background. Studies in musicians and their families have highlighted the contribution of loci (e.g., 4q22) and specific genes (vasopressin receptor 1α and serotonin transporter). The latter two are also associated with dancing. Although few studies have investigated visual arts, they appear to be influenced by genetic differences, which could explain the increased prevalence of synesthesia in artists and individuals with autism. Lastly, although genes play an important role in creativity and art, epigenetics and the environment should not be overlooked. The genetic exploration of artistic creativity may provide useful knowledge on cognition, behavior and brain function. It may also enable targeted and personalized art therapy in health and disease. © 2021 The Author(s).
Λέξεις-κλειδιά:
alpha 1 antitrypsin; brain derived neurotrophic factor; neu differentiation factor; serotonin; serotonin transporter; unclassified drug; vasopressin; vasopressin receptor; vasopressin receptor 1alpha, altruism; art; art therapy; Article; autism; behavior; brain function; cognition; creativity; dancing; dopaminergic system; environment; epigenetics; family; gene expression; gene locus; genetic association; genetic background; genetic difference; genetics; human; mental disease; music; musician; phenotype; prevalence; serotoninergic system; synesthesia; genetics; genotype; synesthesia, Art; Creativity; Dancing; Genotype; Humans; Music; Synesthesia
