Τίτλος:
Isolation of candida auris from cystic fibrosis patient, Greece, april 2019
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
We report the first isolation of Candida auris in Greece from a sputum culture of a cystic fibrosis patient in their 20s under posaconazole treatment. The pathogen was identified as C. duobushaemulonii by VITEK2YST, but as C. auris by MALDI-TOF MS. This case underscores the need for species-level identification of all non-albicans Candida (NAC) isolates from cystic fibrosis patients and patients with predisposing factors to fungal infection. © 2019, European Centre for Disease Prevention and Control (ECDC). All rights reserved.
Συγγραφείς:
Stathi, A.
Loukou, I.
Kirikou, H.
Petrocheilou, A.
Moustaki, M.
Velegraki, A.
Zachariadou, L.
Περιοδικό:
Eurosurveillance
Εκδότης:
European Centre for Disease Prevention and Control (ECDC)
Λέξεις-κλειδιά:
amphotericin B; anidulafungin; caspofungin; ciprofloxacin; colistin; fluconazole; flucytosine; internal transcribed spacer; isavuconazole; itraconazole; ivacaftor plus lumacaftor; micafungin; posaconazole; tobramycin; antifungal agent; antiinfective agent; posaconazole; triazole derivative, antifungal susceptibility; Article; Candida; Candida auris; Candida duobushaemulonii; case report; chronic disease; clinical article; clinical evaluation; coughing; cystic fibrosis; disease exacerbation; disease predisposition; drug withdrawal; fungus identification; fungus isolation; Greece; human; immunosuppressive treatment; lung aspergillosis; lung disease; male; matrix assisted laser desorption ionization time of flight mass spectrometry; minimum inhibitory concentration; mycosis; nonhuman; nucleotide sequence; patient compliance; Pseudomonas infection; pulmonary candidiasis; species identification; sputum; symptom; treatment duration; complication; cystic fibrosis; DNA sequence; drug effect; isolation and purification; matrix-assisted laser desorption-ionization mass spectrometry; microbial sensitivity test; microbiological examination; microbiology; phylogeny; procedures; species difference; treatment outcome; young adult, Anti-Bacterial Agents; Antifungal Agents; Candida; Cystic Fibrosis; Greece; Humans; Microbial Sensitivity Tests; Mycological Typing Techniques; Phylogeny; Sequence Analysis, DNA; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sputum; Treatment Outcome; Triazoles; Young Adult
DOI:
10.2807/1560-7917.ES.2019.24.29.1900400
