Τίτλος:
Molecular epidemiology of endemic carbapenem-resistant gram-negative bacteria in an intensive care unit
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The molecular epidemiology of endemic carbapenem-resistant Klebsiella pneumoniae (CRKP), carbapenem-resistant Pseudomonas aeruginosa (CRPA), and carbapenem-resistant Acinetobacter baumannii (CRAB) in an intensive care unit located in an endemic area with high rates of resistance was investigated. A CRPA strain producing VIM and KPC concurrently was detected for the first time in an endemic area. CRKP strains producing K. pneumoniae carbapenemase predominated and were mainly assigned to the "hyperepidemic Greek clone." Predominant OXA-23-like producing CRAB strains were assigned to multiple pulsotypes. © 2019 Mary Ann Liebert, Inc., publishers.
Συγγραφείς:
Karampatakis, T.
Tsergouli, K.
Politi, L.
Diamantopoulou, G.
Iosifidis, E.
Antachopoulos, C.
Karyoti, A.
Mouloudi, E.
Tsakris, A.
Roilides, E.
Περιοδικό:
Microbial Drug Resistance: Mechanism, Epidemiology, and Disease
Εκδότης:
Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA
Λέξεις-κλειδιά:
carbapenem; carbapenemase; antiinfective agent; bacterial protein; beta lactamase; carbapenem derivative; carbapenemase, Article; bacterial strain; carbapenem resistance; carbapenem resistant Acinetobacter baumannii; carbapenem resistant Klebsiella pneumoniae; carbapenem resistant Pseudomonas aeruginosa; intensive care unit; molecular epidemiology; nonhuman; priority journal; Acinetobacter baumannii; Acinetobacter infection; classification; drug effect; endemic disease; gene expression; genetics; Greece; human; intensive care unit; isolation and purification; Klebsiella infection; Klebsiella pneumoniae; metabolism; microbial sensitivity test; microbiology; molecular epidemiology; multidrug resistance; phylogeny; Pseudomonas aeruginosa; Pseudomonas infection; pulsed field gel electrophoresis, Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Endemic Diseases; Gene Expression; Greece; Humans; Intensive Care Units; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections
DOI:
10.1089/mdr.2018.0266
