Τίτλος:
Splenic granulomatous lesions in immunocompetent pediatric patients with visceral leishmaniasis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Visceral focal lesions are rarely encountered in patients with leishmaniasis despite the fact that splenomegaly, and to a lesser extent hepatomegaly, predominate among the clinical features of the disease. We present, using high resolution ultrasonography, the first 3 reported cases of focal splenic involvement in immunocompetent children with visceral leishmaniasis. All patients showed a prompt response to the conventional anti-leishmanial treatment administered. This favorable outcome indicates that localized splenic lesions should not be considered as a poor prognostic factor and that alteration of the standard anti-leishmanial regimens is not justified.
Συγγραφείς:
Fretzayas, A.
Moustaki, M.
Kitsiou, S.
Mathioudakis, J.
Karpathios, T.
Περιοδικό:
Scandinavian Journal of Infectious Diseases
Λέξεις-κλειδιά:
amphotericin B lipid complex; antileishmanial agent; ceftazidime; meglumine antimonate, article; case report; child; clinical feature; drug response; echography; granulomatosis; hepatomegaly; human; immunocompetence; intestine injury; male; prognosis; spleen injury; splenomegaly; treatment outcome; visceral leishmaniasis, Antiprotozoal Agents; Child; Child, Preschool; Granuloma; Humans; Immunocompetence; Infant; Leishmaniasis, Visceral; Male; Meglumine; Organometallic Compounds; Prognosis; Splenic Diseases; Treatment Outcome
DOI:
10.1080/00365540110027141
