Τίτλος:
The chemical profile of pyrrolizidine alkaloids from selected greek endemic boraginaceae plants determined by gas chromatography/mass spectrometry
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Four Greek endemic Boraginaceae plants, Onosma erecta Sibth. & Sm., Onosma kaheirei Teppner, Onosma leptantha Heldr., and Cynoglossum columnae L. (aerial parts), were screened for their content of pyrrolizidine alkaloids (PAs). TLC with the Mattocks-Molyneux visualization reagent was used as a preliminary qualitative test for PA or PA N-oxide detection. The extracts of the species found to contain PAs and their N-oxides were further analyzed by GC/MS, so as to identify their structures by means of the mass spectra and retention index values of known PAs already published in the literature. Twenty-three PAs were identified. For additional peaks, recognized as possible PAs by their MS pattern, no exact structures were tentatively suggested, as a result of lack of matching literature data. Furthermore, a quantitative PA profile of the species was obtained.
Συγγραφείς:
Damianakos, H.
Jeziorek, M.
Pietrosiuk, A.
Chinou, I.
Περιοδικό:
JOURNAL OF AOAC. INTERNATIONAL
Εκδότης:
AOAC International
Λέξεις-κλειδιά:
Alkaloids; Antennas; Chromatographic analysis; Gas plants; Mass spectrometry; Metabolites, Aerial parts; Chemical profiles; Gas chromatography/Mass spectrometry; Literature data; Mass spectra; Pyrrolizidine alkaloid; Qualitative test; Retention index, Gas chromatography, plant extract; pyrrolizidine alkaloid, Boraginaceae; chemistry; Greece; isolation and purification; mass fragmentography; procedures, Boraginaceae; Gas Chromatography-Mass Spectrometry; Greece; Plant Extracts; Pyrrolizidine Alkaloids
DOI:
10.5740/jaoacint.SGEDamianakos
