Περίληψη:
Objectives. To evaluate the reliability of the OMERACT paediatric
ultrasound (US) synovitis definitions and scoring system in JIA.
Methods. Thirteen sonographers analysed 75 images for the
presence/absence of elementary lesions (binary scoring) and for grading
synovitis, synovial hypertrophy, effusion and Doppler signals. Static US
images of the second metacarpophalangeal joint (MCP-II), wrist, elbow,
knee and ankle in JIA patients at different ages and different disease
stages were collected with standardized scanning by two experienced
sonographers. Intra- and inter-reader reliability were analysed with
kappa coefficients.
Results. Intra-reader reliability was good for binary scoring (Cohen’s
kappa 0.62, range 0.47-0.75), synovitis and synovial hypertrophy;
excellent for Doppler signals (quadratic weighted kappa 0.77, 0.66-0.86;
0.76, 0.61-0.84; and 0.87, 0.77-0.94, respectively); and moderate for
effusion (0.55, 0.24-0.76). Inter-reader reliability was good for
synovitis and synovial hypertrophy (Light’s kappa 0.68, 95% CI: 0.61,
0.75 and 0.63, 0.54-0.71, respectively), excellent for Doppler signals
(0.85, 95% CI: 0.77, 0.90), and moderate for binary scoring and
effusion (0.48, 95% CI: 0.36, 0.64 and 0.49, 0.40-0.60, respectively).
We obtained the best scores for the knee (0.71, 0.54-0.85) except for
Doppler signals, with reliability higher for MCP-II. We found a trend
toward better results in older children.
Conclusions. This is the first study establishing the reliability of the
OMERACT paediatric US synovitis definitions and scoring system in the
five most commonly affected joints in JIA. The reliability was good
among a large group of sonographers. These results support the
applicability of these definitions and scoring system in clinical
practice and multicentre studies.
Συγγραφείς:
Rossi-Semerano, Linda
Breton, Sylvain
Semerano, Luca and
Boubaya, Marouane
Ohanyan, Haykanush
Bossert, Marie
Boiu,
Sorina
Chatelus, Emmanuel
Durand, Geraldine
Jean, Sylvie and
Goumy, Laurence
Mathiot, Anne
Mouterde, Gael
Nugues,
Frederique
Hennia, Ahmed Ould
Rey, Benedicte
Von Scheven,
Annette
Sparsa, Laetitia
Devauchelle-Pensec, Valerie and
Jousse-Joulin, Sandrine
