Τίτλος:
Spectrum of Causative Pathogens and Resistance Rates to Antibacterial
Agents in Bacterial Prostatitis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective: To evaluate spectrum and resistance rates to antibacterial
agents in causative pathogens of bacterial prostatitis in patients from
Southern Europe, the Middle East, and Africa. Materials: 1027 isolates
from cultures of urine or expressed prostatic secretion, post-massage
urine or seminal fluid, or urethral samples were considered. Results:
Escherichia colt (32%) and Enterococcus spp. (21%) were the most
common isolates. Other Gram-negative, Gram-positive, and atypical
pathogens accounted for 22%, 20%, and 5%, respectively. Resistance
was <15% for piperacillin/tazobactam and carbapenems (both
Gram-negative and -positive pathogens); <5% for glycopeptides against
Gram-positive; 7%, 14%, and 20% for aminoglycosides, fosfomycin, and
macrolides against Gram-negative pathogens, respectively; 10% for
amoxicillin/clavulanate against Gram-positive pathogens; <20% for
cephalosporins and fluoroquinolones against to Gram-negative pathogens
(higher against Gram-positive pathogens); none for macrolides against
atypical pathogens, but 20% and 27% for fluoroquinolones and
tetracyclines. In West Africa, the resistance rates were generally
higher, although the highest rates for ampicillin, cephalosporins, and
fluoroquinolones were observed in the Gulf area. Lower rates were
observed in Southeastern Europe. Conclusions: Resistance to antibiotics
is a health problem requiring local health authorities to combat this
phenomenon. Knowledge of the spectrum of pathogens and antibiotic
resistance rates is crucial to assess local guidelines for the treatment
of prostatitis.
Συγγραφείς:
Trinchieri, Alberto
Abdelrahman, Khalid Mohammed
Bhatti, Kamran
Hassan
Bello, Jibril O.
Das, Krishanu
Gatsev, Ognyan and
Gergova, Ivanka
Magri, Vittorio
Mourmouras, Nikos and
Mourmouris, Panagiotis
Murdeshwar, Soni
Perletti, Gianpaolo and
Saltirov, Iliya
Sissoko, Idrissa
Stamatiou, Konstantinos and
Buchholz, Noor
Περιοδικό:
DIAGNOSTIC ONCOLOGY
Λέξεις-κλειδιά:
bacterial prostatitis; Escherichia coli; Enterobacteriacae;
Gram-positive pathogens; antibiotic; resistance
DOI:
10.3390/diagnostics11081333
