Τίτλος:
Successful trovafloxacin prophylaxis against experimental streptococcal
aortic valve endocarditis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Single-dose trovafloxacin (15 mg/kg given intravenously [i.v.]) and
ampicillin (40 mg/kg given i.v.) protected 38 and 33% of animals
challenged with an ampicillin-tolerant strain of Streptococcus oralis,
respectively. As a double-dose regimen, trovafloxacin afforded total
protection (100%; P < 0.001 versus controls). Trovafloxacin is the
first fluoroquinolone effective in preventing experimental streptococcal
endocarditis.
Συγγραφείς:
Katsarolis, I
Pefanis, A
Iliopoulos, D
Siaperas, P and
Karayiannakos, P
Giamarellou, H
Περιοδικό:
Antimicrobial Agents and Chemotherapy
Εκδότης:
AMER SOC MICROBIOLOGY
DOI:
10.1128/AAC.44.9.2564-2566.2000
