Περίληψη:
Background: Evidence on the short-term effects of fine and coarse particles on morbidity in Europe is scarce and inconsistent. Objectives: We aimed to estimate the association between daily concentrations of fine and coarse particles with hospitalizations for cardiovascular and respiratory conditions in eight Southern European cities, within the MED-PARTICLES project. Methods: City-specific Poisson models were fitted to estimate associations of daily concentrations of particulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5), ≤ 10 (PM10), and their difference (PM2.5-10) with daily counts of emergency hospitalizations for cardiovascular and respiratory diseases. We derived pooled estimates from random-effects meta-analysis and evaluated the robustness of results to co-pollutant exposure adjustment and model specification. Pooled concentration-response curves were estimated using a meta-smoothing approach. Results: We found significant associations between all PM fractions and cardiovascular admissions. Increases of 10 μg/m3 in PM2.5, 6.3 μg/m3 in PM2.5-10, and 14.4 μg/m3 in PM10 (lag 0-1 days) were associated with increases in cardiovascular admissions of 0.51% (95% CI: 0.12, 0.90%), 0.46% (95% CI: 0.10, 0.82%), and 0.53% (95% CI: 0.06, 1.00%), respectively. Stronger associations were estimated for respiratory hospitalizations, ranging from 1.15% (95% CI: 0.21, 2.11%) for PM10 to 1.36% (95% CI: 0.23, 2.49) for PM2.5 (lag 0-5 days). Conclusions: PM2.5 and PM2.5-10 were positively associated with cardiovascular and respiratory admissions in eight Mediterranean cities. Information on the short-term effects of different PM fractions on morbidity in Southern Europe will be useful to inform European policies on air quality standards.
Συγγραφείς:
Stafoggia, M.
Samoli, E.
Alessandrini, E.
Cadum, E.
Ostro, B.
Berti, G.
Faustini, A.
Jacquemin, B.
Linares, C.
Pascal, M.
Randi, G.
Ranzi, A.
Stivanello, E.
Forastiere, F.
Angelini, P.
Bisanti, L.
Catrambone, M.
Chiusolo, M.
Davoli, M.
de’ Donato, F.
Demaria, M.
Gandini, M.
Grosa, M.
Ferrari, S.
Pandolfi, P.
Pelosini, R.
Perrino, C.
Pietrodangelo, A.
Pizzi, L.
Poluzzi, V.
Priod, G.
Rowinski, M.
Scarinzi, C.
Zauli-Sajani, S.
Dimakopoulou, K.
Elefteriadis, K.
Katsouyanni, K.
Kelessis, A.
Maggos, T.
Michalopoulos, N.
Pateraki, S.
Petrakakis, M.
Rodopoulou, S.
Sypsa, V.
Artiñano, B.
Barrera-Gómez, J.
Basagaña, X.
de la Rosa, J.
Diaz, J.
Karanasiou, A.
Pey, J.
Querol, X.
Sunyer, J.
Tobias, A.
Bidondo, M.
Declercq, C.
Le Tertre, A.
Lozano, P.
Medina, S.
Pascal, L.
MED-PARTICLES Study Group
