Τίτλος:
Silkmoth chorion gene regulation revisited: Promoter architecture as a key player
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Regulation of silkmoth chorion genes has long been used as a model system for studying differen tial gene expression. The large numbers of genes, their overlapping expression patterns and the over all complexity of the system hinted towards an elaborate mechanism for transcriptional control. Recent studies, however, offer evidence of a mole cular pathway governed by the interplay between two general transcription factors, CCAAT enhancer binding proteins (C/EBP) and GATA, an architectural protein, high mobility group A and a chromatin remod-eller, chromo-helicase/ATPase-DNA binding protein 1. In this review we present a parsimonious model that adequately describes regulation of transcription across all temporally regulated chorion genes, and propose a role for promoter architecture. © 2009 The Authors.
Συγγραφείς:
Lecanidou, R.
Papantonisf, A.
Περιοδικό:
Insect Molecular Biology
Λέξεις-κλειδιά:
basic leucine zipper transcription factor; CCAAT enhancer binding protein; chorion proteins; egg protein; high mobility group A protein; insect protein; transcription factor GATA, animal; female; gene; gene expression; genetics; nucleosome; oocyte development; physiology; promoter region; review; signal transduction; silkworm; vitellogenesis, Animals; Basic-Leucine Zipper Transcription Factors; Bombyx; CCAAT-Enhancer-Binding Proteins; Egg Proteins; Female; GATA Transcription Factors; Gene Expression; Genes, Insect; HMGA Proteins; Insect Proteins; Nucleosomes; Oogenesis; Promoter Regions, Genetic; Signal Transduction; Vitellogenesis, Bombyx mori; Insectivora
DOI:
10.1111/j.1365-2583.2009.00969.x
