Τίτλος:
In vivo performance of osteoactivated cellulose-based scaffolds in bony critical-Size defects
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A study was conducted to demonstrate in vivo performance of osteoactivated cellulose-based scaffolds in bony critical-size defects. The study focused on investigating the capacity of a sodium silicate coating applied on knitted cellulose as a long-term depot for a slow drug-release and the incorporation of pamidronate and strontium in sodium silicate coatings. It was observed that the cellulose yarns were randomly ordered according to the knitting patterns. The macropores obtained from the knitting process were filled with resin as they remained open during the coating procedure. The micropores between the monofilaments of the sodium silicate-coated yarn were filled with sodium silicate gel. Scanning electron microscopy (SEM) micrographs also revealed the disappearance of sodium silicate during the whole period of investigation.
Συγγραφείς:
Ponader, S.
Brandt, H.
Vairaktaris, E.
Von Wilmowsky, C.
Göthel, W.
Lutz, R.
Schlegel, K.A.
Neukam, F.W.
Greil, P.
Müller, F.A.
Nkenke, E.
Περιοδικό:
Advanced Engineering Materials
Λέξεις-κλειδιά:
Coating procedures; In-vivo; Knitting process; Macropores; Micropores; Pamidronate; SEM; Sodium silicate; Sodium silicate gel, Agricultural products; Cellulose; Gelation; Resins; Scaffolds; Scanning electron microscopy; Silicates; Strontium, Sodium, Agriculture; Cellulose; Gelation; Scaffolds; Scanning Electron Microscopy; Silicates; Sodium; Strontium; Synthetic Polymers
DOI:
10.1002/adem.200800437
