Τίτλος:
Exhaled breath condensate acidification occurs during surgery for abdominal cancer
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background/Aim: Acidification of exhaled breath condensate (EBC), reflecting airway inflammation and oxidative stress, has been reported in lung cancer patients undergoing lobectomy. We undertook this study to examine EBC pH changes during surgery for abdominal cancer. Patients and Methods: EBC pH was measured from 20 patients undergoing abdominal cancer resection before and during surgery. Repeated-measures of ANOVA and randomeffects linear models were applied to compare mean EBC pH values in samples collected at different times. Cox and linear regression models were used to determine the association of EBC pH with occurrence of acute bronchospasm intraoperatively and the duration of hospitalization. Results: Significant acidification of EBC was observed during surgery (p=0.007) associated with 0.77% (95% confidence interval=-0.14-1.68, p-value=0.097) increase in the risk for developing acute bronchospasm, after adjustment for potential confounders. Conclusion: EBC acidification occurs in patients undergoing abdominal cancer resection and is associated with the occurrence of acute bronchospasm intraoperatively.
Συγγραφείς:
Mahairidou, A.
Rodopoulou, S.
Tomos, I.
Maratou, E.
Manali, E.
Raptakis, T.
Papiris, S.A.
Karakatsani, A.
Περιοδικό:
ANTICANCER RESEARCH
Εκδότης:
International Institute of Anticancer Research
Λέξεις-κλειδιά:
abdominal cancer; abdominal surgery; acidification; acidity; acute disease; adult; Article; artificial ventilation; blood pH; bronchospasm; cancer patient; cancer surgery; clinical article; comparative study; controlled study; disease association; exhaled breath condensate acidification; female; hospitalization; human; intraoperative period; male; middle aged; pH measurement; preoperative evaluation; priority journal; respiratory tract parameters; risk factor; smoking; surgical patient; Abdominal Neoplasms; abdominal surgery; adverse effects; aged; breath analysis; Bronchial Spasm; exhalation; gynecologic surgery; intraoperative monitoring; length of stay; pathophysiology; pH; predictive value; procedures; proportional hazards model; statistical model; time factor; treatment outcome; urologic surgery; very elderly, Abdominal Neoplasms; Adult; Aged; Aged, 80 and over; Breath Tests; Bronchial Spasm; Digestive System Surgical Procedures; Exhalation; Female; Gynecologic Surgical Procedures; Humans; Hydrogen-Ion Concentration; Length of Stay; Linear Models; Male; Middle Aged; Monitoring, Intraoperative; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Time Factors; Treatment Outcome; Urologic Surgical Procedures
DOI:
10.21873/anticanres.11700
