Τίτλος:
Autoimmunity and coxsackievirus infection in primary Sjogren's syndrome
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Exocrine gland epithelial cells are the target of autoimmune pathology
in primary Sjogren’s syndrome (pSS). Their activated phenotype has
incited the notion that they are infected by a virus. We recently
presented evidence that coxsackieviruses may persistently infect the
salivary glands of pSS patients. We hypothesize that coxsackieviruses
may play a permissive role for the perpetuation and possibly the
induction of autoimmune disease in pSS.
Συγγραφείς:
Triantafyllopoulou, A
Moutsopoulos, HM
Εκδότης:
THE NEW YORK ACADEMY OF SCIENCES
Τίτλος συνεδρίου:
AUTOIMMUNITY: CONCEPTS AND DIAGNOSIS AT THE CUTTING EDGE
Λέξεις-κλειδιά:
Sjogren’s syndrome; autoimmunity; coxsackieviruses; epithelial cell
activation
DOI:
10.1196/annals.1313.090
