Τίτλος:
Prognostic factors in thymic epithelial tumors undergoing complete
resection
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background. The prognostic factors in thymic epithelial tumors (TET) are
investigated within a 27-year period in 104 patients submitted to
surgical and pathologic complete resection of TET with a mean age of 53
+/- 14.6 years and a male to female ratio of 0.73.
Methods. The medical records of all patients were reviewed and six
variables that could affect the short-term and long-term survival were
entered into a Cox regression model. Follow-up was obtained from medical
records and telephone contacts up to September 2004 or until the
patient’s death.
Results. Overall 5-year and 10-year survival was 83% and 78%,
respectively. Univariate Cox regression analysis showed that long
survival was affected by the age of the patient at the time of
operation, the response of myasthenia gravis to the operation, the tumor
recurrence, the histologic type according to the World Health
Organization (WHO) classification, and the Masaoka stage. Multivariate
analysis revealed that recurrence of the tumor (P = 0.001), Nlasaoka
stages II or III (p < 0.001), elder age of the patient at the time of
operation (p = 0.045), and presence of the WHO histologic types B2 or B3
(p = 0.05) were bad prognostic factors.
Conclusions. Recurrence of the tumor, the Masaoka staging, the WHO
histologic type, and the age of the patient at the time of operation
were the most important prognosticators for patients with TET submitted
to complete resection of their tumor.
Συγγραφείς:
Zisis, C
Rontogianni, D
Tzavara, C
Stefanaki, K and
Chatzimichalis, A
Loutsidis, A
Iliadis, K
Kontaxis, A and
Dosios, T
Bellenis, I
Περιοδικό:
The Annals of Thoracic Surgery
Εκδότης:
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI:
10.1016/j.athoracsur.2005.03.093
