Τίτλος:
Bronchial challenges in athletes applying to inhale a beta(2)-agonist at
the 2004 Summer Olympics
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background: The International Olympic Committee Medical Commission
required a medical justification for athletes to inhale a
beta(2)-agonist before an event at the Summer Games in Athens in 2004.
Objective: We sought to establish the percentage of athletes applying to
use an inhaled beta(2)-agonist on the basis of the results of objective
tests to establish a diagnosis of asthma or exercise-induced
bronchoconstriction. We also sought to compare this percentage with the
percentage of athletes simply notifying the intention to use a
beta(2)-agonist at the previous Summer Games in Sydney in 2000.
Methods: An analysis was made of tests that measured the change in FEV1
in response to a bronchodilator or in response to a provoking stimulus,
such as exercise, eucapnic voluntary hyperpnea, hypertonic saline, or
methacholine.
Results: Ten thousand six hundred fifty-three athletes competed in
Athens; 4.2% were approved to use a beta(2)-agonist, and 0.4% were
rejected. This approval rate was 26% less than the notifications in
2000 in Sydney (5.7%). Compared with Sydney 2000, there was a
significant reduction of submissions and approvals for athletes from the
United States, New Zealand, Australia, and Canada and in triathlon and
swimming sports.
Conclusion: The need to provide objective testing has resulted in a
reduction in the number of athletes seeking approval to use an inhaled
beta(2)-agonist. Objective evidence has provided information for the
doctor that is likely to improve the health of the athlete because many
athletes appeared to be undertreated at the time of testing.
Clinical implications: We show that documentation of airway narrowing in
athletes, particularly in response to exercise or surrogate stimuli for
exercise, aids in the diagnosis and management of asthma by providing
evidence of bronchial hyperresponsiveness that will respond to treatment
with inhaled corticosteroids and is usually associated with a reduction
in respiratory symptoms on exercise.
Συγγραφείς:
Anderson, SD
Sue-Chu, M
Perry, CP
Gratziou, C
Kippelen,
P
McKenzie, DC
Beck, KC
Fitch, KD
Περιοδικό:
Allergy: European Journal of Allergy and Clinical Immunology
Λέξεις-κλειδιά:
athletes; asthma; beta(2)-agonist; bronchial provocation; exercise;
eucapnic hyperpnea; methacholine
DOI:
10.1016/j.jaci.2005.12.1355
