Περίληψη:
Objective: Τo investigate the effect of an asthma care educational program for children and adolescents with asthma, on adherence to asthma control treatment and on clinical indices. Methods: Individuals newly diagnosed with asthma, aged 4–16 years, randomized to the intervention and control group. The participants were monitored for 6 weeks. At baseline, before the initiation of inhaled corticosteroids/long-acting beta2-agonist (ICS/LABA), the intervention group attended the educational program; the control group received the usual care. Both groups were equipped with electronic monitoring devices for measuring adherence. Spirometry, exhaled nitric oxide fraction (FeNO), and asthma control test (ACT) score were measured in both groups in the pre and post-ICS/LABA initiation visit. Results: Seventy-eight participants were enrolled in this study (n = 39 to each group). Median percentage of adherence was 73% for the total sample, and 80% and 68% in intervention and control group, respectively (p < 0.001). In multivariate analysis, the program was positively associated with improved adherence (p < 0.001). ICS/LABA had a positive effect on spirometric indices, FeNO, and ACT score, whilst the educational program did not improved significantly the above variables. Conclusions: Establishing and increasing adherence is challenging. An asthma care educational program is associated with greater short-term adherence during a period of active monitoring. © 2019, © 2019 Taylor & Francis Group, LLC.
Συγγραφείς:
Koumpagioti, D.
Boutopoulou, B.
Priftis, K.N.
Douros, K.
Λέξεις-κλειδιά:
beta 2 adrenergic receptor stimulating agent; corticosteroid; long acting drug; nitric oxide; antiasthmatic agent; beta adrenergic receptor stimulating agent; corticosteroid; nitric oxide, adolescent; Article; asthma; Asthma Control Test; child; controlled study; corticosteroid therapy; disease control; female; follow up; forced expiratory volume; forced vital capacity; fractional exhaled nitric oxide; human; intervention study; major clinical study; male; medication compliance; patient compliance; patient monitoring; program effectiveness; randomized controlled trial; spirometry; asthma; breath analysis; exhalation; medication compliance; metabolism; pathophysiology; patient education; preschool child; vital capacity, Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Breath Tests; Child; Child, Preschool; Exhalation; Female; Forced Expiratory Volume; Humans; Male; Medication Adherence; Nitric Oxide; Patient Education as Topic; Spirometry; Vital Capacity
