Τίτλος:
Optical Biometry Derived Axial Length Measurements Following Intravitreal Anti-Vascular Endothelial Growth Factor Treatment for Macular Edema
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose: To evaluate axial length (AL) alterations in patients with macular disease over the course of intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment. Methods: In this prospective, comparative study, 33 patients with macular edema underwent unilaterally intravitreal anti-VEGF therapy and were followed for two months; the contralateral eyes were considered as controls. Central retinal thickness (CRT) was measured with spectral-domain optical coherence tomography and AL with an IOL-Master optical biometer. Results: CRT of the treated eyes decreased by 35.33 ± 65.59 μm (range, –222.00–67 μm), while AL increased by 0.008 ± 0.062 mm (range, –0.11–0.18 mm). CRT of the control group decreased by 9.82 ± 65.40 μm (range, –203–182 μm), and AL increased by 0.011 ± 0.129 mm (range, –0.20–0.67 mm). No significant correlation was detected between CRT and AL parameters (rhos=0.026, P=0.882). Conclusions: Anti-VEGF administration has no significant impact on optical biometry-derived AL measurements. © Taylor & Francis.
Συγγραφείς:
Kymionis, G.D.
Giarmoukakis, A.
Apostolidi, I.K.
Blazaki, S.V.
Tsoulnaras, K.I.
Moschandrea, J.
Panagopoulou, S.
Tsilimbaris, M.K.
Περιοδικό:
Seminars in Ophthalmology
Εκδότης:
Taylor and Francis Ltd.
Λέξεις-κλειδιά:
ranibizumab; angiogenesis inhibitor; ranibizumab; vasculotropin A, aged; Article; biometry; central retinal thickness; clinical article; comparative study; controlled study; eye axis length; female; follow up; human; macular edema; male; observational study; priority journal; prospective study; spectral domain optical coherence tomography; antagonists and inhibitors; biometry; diagnostic imaging; eye axis length; eye fundus; fluorescence angiography; intravitreal drug administration; macular edema; optical coherence tomography; pathology; pathophysiology; procedures; retina macula lutea; visual acuity, Aged; Angiogenesis Inhibitors; Axial Length, Eye; Biometry; Female; Fluorescein Angiography; Fundus Oculi; Humans; Intravitreal Injections; Macula Lutea; Macular Edema; Male; Prospective Studies; Ranibizumab; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity
DOI:
10.1080/08820538.2017.1303520
