Τίτλος:
Salvage of the Foot for Recurrent Malignant Peripheral Nerve Sheath Tumor
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Malignant peripheral nerve sheath tumors are rare soft tissue tumors accounting for 3% to 10% of all soft tissue tumors. They are strongly related to neurofibromatosis type 1, an autosomal dominant disease, and are characterized by aggressive biologic behavior, high local recurrence rates, and frequent metastases. Although the major nerves of the lower extremities are a common location of these tumors, scarce cases have been reported of malignant peripheral nerve sheath tumors involving the interdigital nerves of the foot. We report the case of a patient with non-neurofibromatosis type 1 and a recurrent malignant peripheral nerve sheath tumor of the first interdigital nerve of the foot treated successfully with limb salvage surgery with wide resection margins and reconstruction with an autogenous fibula graft. © 2017 American College of Foot and Ankle Surgeons
Συγγραφείς:
Rozis, M.
Papadelis, E.
Mavrogenis, A.
Koufos, S.
Polyzois, V.
Pneumaticos, S.
Περιοδικό:
Journal of Foot and Ankle Surgery
Εκδότης:
Academic Press Inc.
Λέξεις-κλειδιά:
gadolinium chelate; protein S 100, aged; Article; bone biopsy; cancer surgery; case report; clinical article; clinical examination; female; fibromatosis; follow up; foot; foot pain; foot radiography; foot surgery; fracture healing; human; human cell; human tissue; limb salvage; malignant neurilemoma; malignant peripheral nerve sheath tumor; metatarsal bone; nuclear magnetic resonance imaging; postoperative period; autograft; bone transplantation; fibula; foot; immunohistochemistry; limb salvage; needle biopsy; nerve sheath tumor; neurofibromatosis type 1; pathology; peripheral nerve tumor; procedures; reconstructive surgery; risk assessment; soft tissue tumor; treatment outcome, Aged; Autografts; Biopsy, Needle; Bone Transplantation; Female; Fibula; Follow-Up Studies; Foot; Humans; Immunohistochemistry; Limb Salvage; Nerve Sheath Neoplasms; Neurofibromatosis 1; Peripheral Nervous System Neoplasms; Reconstructive Surgical Procedures; Risk Assessment; Soft Tissue Neoplasms; Treatment Outcome
DOI:
10.1053/j.jfas.2017.04.029
