Τίτλος:
Embryonal tumor with abundant neuropil and true rosettes: A systematic literature review and report of 2 new cases
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Embryonal tumor with abundant neuropil and true rosettes has been recently defined as a distinct central nervous system embryonal neoplasm, although it was initially regarded as a subtype of central nervous system primitive neuroectodermal tumor. To date 70 cases have been reported. We have performed a literature review and we present 2 new cases. Analysis of the reported data revealed that radiotherapy, tumor excision and high-dose adjuvant chemotherapy with sequential autologous hematopoietic stem cell rescue have a prognostic significance.
Συγγραφείς:
Alexiou, G.A.
Stefanaki, K.
Vartholomatos, G.
Sfakianos, G.
Prodromou, N.
Moschovi, M.
Περιοδικό:
Journal of Child Neurology
Εκδότης:
SAGE Publications Inc.
Λέξεις-κλειδιά:
chaperonin 60; choline; cisplatin; creatine; cyclophosphamide; cytokeratin 18; cytokeratin 8; cytokeratin AE1; cytokeratin AE3; epithelial membrane antigen; etoposide; glial fibrillary acidic protein; heat shock protein 27; heat shock protein 40; heat shock protein 70; heat shock protein 90; heat shock protein 90alpha; inositol; methotrexate; n acetylaspartic acid; neurofilament protein; protein bcl 2; protein p53; synaptophysin; tubulin; unclassified drug; vincristine, adjuvant chemotherapy; anterior fontanel; article; brain atrophy; brain fourth ventricle; brain ventricle peritoneum shunt; cancer surgery; case report; computer assisted tomography; DNA determination; embryo cell; embryonal tumor with abundant neuropil and true rosette; follow up; hematopoietic stem cell; histology; human; hydrocephalus; immunohistochemistry; immunoreactivity; infant; intracranial pressure; male; missense mutation; mitosis rate; nerve cell differentiation; neuroectoderm tumor; nuclear magnetic resonance spectroscopy; ornithine transcarbamylase deficiency; patient referral; physical examination; posterior fossa; priority journal; protein expression; rhabdoid tumor; seizure; teratoma; tumor suppressor gene; vomiting; weight reduction; Brain Neoplasms; Neoplasms, Germ Cell and Embryonal; neuropil; pathology, Brain Neoplasms; Humans; Infant; Male; Neoplasms, Germ Cell and Embryonal; Neuropil
DOI:
10.1177/0883073812471434
