Manual high-dose regional intraoperative thrombolysis of lower extremity emboli after open repair of a ruptured abdominal aortic aneurysm

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3129889 28 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Manual high-dose regional intraoperative thrombolysis of lower extremity emboli after open repair of a ruptured abdominal aortic aneurysm
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
We describe a case of high-dose regional intraoperative thrombolysis subsequent to mechanical thrombectomy for the treatment of postoperative distal extremity embolization of the right lower limb owing to open repair of a ruptured abdominal aortic aneurysm. Mechanical thrombectomy was performed from the popliteal artery but residual embolic occlusion of all three tibial arteries remained. The limb was elevated, exsanguinated, and a blood cuff was placed below the knee and inflated to suprasystolic pressure to isolate the limb from systemic circulation. An 18-gauge infusion catheter was introduced to the exposed dorsalis pedis artery. Subsequently, the exposed great saphenous vein was cannulated and drained. A total of 100 mg of recombinant tissue-type plasminogen activator diluted in 500 mL of saline was infused into the anterior tibial artery with a slow hand infusion for 30 minutes. The infusion was continuously collected through the great saphenous cannulation and a closed loop was confirmed by angiogram. The limb was flushed with heparin and saline solution. Infusion catheter was extracted and the great saphenous vein was ligated. Blood cuff was removed, arterial flow was re-established, and a postprocedural arteriogram confirmed successful revascularization. This method may be an alternative to microtibial embolectomy at the foot ankle level after severe lower limb embolization after acute open repair of a ruptured abdominal aortic aneurysm. © 2011 Annals of Vascular Surgery Inc.
Έτος δημοσίευσης:
2011
Συγγραφείς:
Bakoyiannis, C.N.
Kafeza, M.
Economopoulos, K.P.
Tsekouras, N.
Georgopoulos, S.
Papalambros, E.
Περιοδικό:
Annals of Vascular Surgery
Εκδότης:
HANLEY & BELFUS-ELSEVIER INC
Τόμος:
25
Αριθμός / τεύχος:
7
Σελίδες:
981.e13-981.e16
Λέξεις-κλειδιά:
alteplase; heparin, abdominal aorta aneurysm; aged; aneurysm surgery; angiography; aorta graft; artery occlusion; article; blood clot lysis; case report; continuous infusion; dorsal pedal artery; drug megadose; follow up; human; male; mechanical thrombectomy; popliteal artery; priority journal; retroperitoneal hematoma; revascularization; saphenous vein; systemic circulation; tibial artery; vein ligation; venous thromboembolism
Επίσημο URL (Εκδότης):
DOI:
10.1016/j.avsg.2011.03.010
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